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Cofactor.

Yes, there is a chronic wasting disease-themed video game!

Cofactor is a role-playing game that allows you to explore the science, health concerns, ecology, regulations, cultural impact, and ethical considerations surrounding this disease. You navigate a story that changes according to decisions made, location, local regulations, and advances in science, unlocking other roles as you progress.

Frequently Asked Questions

The game's first iteration is meant for Minnesota high school students, so roughly age 14-18. The game has lessons and entertainment for just about everyone, though. Eventually, we would like to open access to all Minnesotans.
Cofactor hits a wave of pilot classrooms across Minnesota in January 2026.
There is a waiting list to pilot Cofactor. Send your teacher this link if you would like them to be added to it!
• Understanding of CWD biology, transmission, and management practices. • Recognition of the roles hunters, agencies, and citizens play in disease control. • Improved confidence and competence for hunting in CWD‑affected zones. • Awareness of career pathways such as natural‑resource management.
If you play the game as part of a class, your feedback will shape future storylines, scenarios, and educational content. If you're not part of a pilot class, watch this page for updates. Wheels are in motion!
A modern web browser with HTML5 video support (Chrome, Firefox, Edge, Safari) is all that’s needed. The game runs entirely online – no downloads required.
Role‑play creates a safe, engaging space where players can explore different perspectives, practice decision‑making, and see the collective impact of individual actions – all essential for effective CWD management.

PRESS

CBS News / WCCO thumbnail

WCCO (CBS News)

“Video game hopes to teach high school students about chronic wasting disease”

Racket logo – MN‑Made video game sets to educate à la Oregon Trail

RACKET

“MN‑Made Video Game Sets to Educate à la Oregon Trail”

Brought to you by:

This project is being developed at the Minnesota Center for Prion Research and Outreach at the University of Minnesota. Funding for this project was provided by the Minnesota Environment and Natural Resources Trust Fund as recommended by the Legislative-Citizen Commission on Minnesota Resources (LCCMR).

MNPRO logo MN Environment and Natural Resources Trust Fund logo